16:50745656 G / A



Annotations

This variant falls on 10 transcripts in 2 genes:

Note: This list may not include additional transcripts in the same gene that the variant does not overlap.
Population Genotype Counts
Population HOM REF HET HOM ALT
AJ 5615 69 1
FIN 11477 2 0
NFE 7735 5 0
Carrier rate in population isolates
Population Rate
AJ 1 in 128
FIN 1 in 4957
Note: Carrier rate for "AJ" was estimated from set of individuals with AJ fraction of at least 90%. Individuals from Northern Finland were removed to estimate the carrier rate for "FIN". Carrier rate is estimated for alternate allele only.
Population Case-Control statistics
IBD
Population IBD AF non-IBD AF Odds Ratio P-value
European (Ashkenazi-Jewish) 0.009655 0.003287 3.61 2.157e-07
Non-Finnish European 0.0004024 0.0001806 1.674 0.57
European (Finnish) 0 0.0001009 5.944 0.3468
Total - - 3.222
[2.367, 4.386]
1.017e-06
CD
Population CD AF non-CD AF Odds Ratio P-value
European (Ashkenazi-Jewish) 0.01294 0.003287 4.639 8.21e-10
Non-Finnish European 0.0006533 0.0001806 2.642 0.2969
European (Finnish) 0 0.0001009 23.67 0.146
Total - - 4.21
[3.088, 5.738]
2.767e-09
UC
Population UC AF non-UC AF Odds Ratio P-value
European (Ashkenazi-Jewish) 0.002143 0.003287 0.8728 0.8223
Non-Finnish European 0.0002897 0.0001806 1.602 0.6845
European (Finnish) 0 0.0001009 9.989 0.2499
Total - - 1.128
[0.7807, 1.63]
0.7725
Note: 95% credible interval for odds ratio is reported in brackets.